This article comprehensively examines Indonesia's economic defense strategy in facing the three poles of global hegemony: Sovereign Power (81 Trillion USD), Transcapital Power (78 Trillion USD), and Technology Power (6 Trillion USD). Using a qualitative literature review methodology enriched with critical geopolitical analysis, the study is built upon three main reference pillars: (1) the thought of Soemitro Djojohadikusumo as documented in the book Soemitro Djojohadikusumo Anti-Colonialism: The Struggle of Indonesian Political Economy Thought (2026); (2) the philosophical framework of Pancasila in its axiological dimension as studied by Sindi Pramita et al. in the Journal on Education (2024); and (3) the global geo economic map of Design Thinking: Defense vs. DominationStrategy (2026). The study finds that Soemitronomics the value-based economic paradigm developed by Soemitro operationalizes seven strategic pillars that directly correspond to the axiological framework of Pancasila's five principles. Results demonstrate that the contemporary programs of President Prabowo Subianto, particularly Free Nutritious Meals (MBG) and the Red and White Village Cooperative, represent the most concrete institutional manifestations of this synthesis. The article concludes that Soemitronomics, in the
multipolar era of 165 trillion USD global power, constitutes not merely an historical academic legacy but an urgent and actionable roadmap for Indonesia's sovereign development
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